Understanding CBD:
CB1 Receptors,
CB2 Receptors &
Hemp Terpenes

Cannabidiol (CBD) has been generating a lot of buzz lately. You've probably noticed CBD oil for sale at your local dispensary, but you might be wondering what it is and how it differs from products produced from the cannabis plant.

Our team here at One Hemp Holistics will help you understand CBD by going over CB1 receptors, CB2 receptors, the benefits of hemp terpenes, as well as some helpful hints to know before you buy!

CB-receptors are two main types of receptors in the human body that interact with cannabinoids. Simply put, they're what CBD interacts with to provide health benefits. They also interact with the THC produced from the cannabis plant to provide a natural high.

CB1 Receptors - Primarily found in your brain

CB2 Receptors - Typically found on immune cells

Understanding CB1 Receptors

CBD and THC both come from a cannabis Sativa plant. These chemical compounds circulate through the bloodstream to the brain, where they activate cannabinoid receptors. Cannabis-derived CBD is non-psychoactive; instead, it potentiates THC by enhancing its effects at CB1 receptors throughout the body. These effects include a mood boost that renders anxiety less overwhelming (desensitization).

CBD Is True Bliss

CBD will increase levels of anandamide in the brain, which is one of the few cannabinoids found naturally in the body. Derived from the Sanskrit word Ananda, anandamide stands for bliss. Studies suggest a CBD product can help with managing anxiety, increase sleep quality, and help with alleviating pain.

Why CBD Works So Well

The reason CBD products work so well is that CBD inhibits FAAH enzymes from breaking anandamide down. As a result, people who take CBD can experience reduced anxiety disorders and other benefits that come with being less anxious, thanks to this inhibitory effect on the FAAH enzyme's activity level.

What Is CBD Isolate, Full Spectrum CBD, & Broad Spectrum CBD?

There are several similarities between all three of these variations of CBD products. These similarities are that CBD manufacturers extract CBD from industrial hemp plants, they're all rich in CBD, have therapeutic effects, and their extraction processes are the same. In addition, these hemp-derived CBD products help address several health conditions that are traditionally managed with prescription medications.

CBD Isolate

CBD Isolate is cannabis that has been refined into a pure CBD product. Therefore, it lacks the other cannabinoids, terpenes, and plant material found in Full Spectrum CBD.

Full Spectrum CBD Oil

Full-spectrum CBD oil contains more than just CBD. It has terpenes, CBD compounds, and other parts of a hemp plant. Our full-spectrum CBD products encourage a healthy lifestyle and contain trace amounts of THC.

Broad Spectrum CBD

Broad-spectrum CBD oil is very similar to full-spectrum because it contains other cannabinoids and parts of the hemp plant. The distinct difference between the two is that broad-spectrum CBD lacks THC levels.

What Is Anandamide?

Taking CBD oil works to regulate various systems of the body without any adverse effects whatsoever. One of these systems is to prevent the FAAH enzyme from breaking down anandamide. Anandamide is the fatty acid neurotransmitter responsible for affecting many different elements, from moods to appetite patterns.

CBD's Healing Powers

  • Pain Relief
  • Body Stiffness & Soreness
  • Chronic Pain
  • Arthritis

Lets Relax
Together With

CBD is one of the chemical compounds found in the cannabis Sativa plant. CBD pills & CBD capsules will reduce stress, promote relaxation, and help manage chronic pain. It works by lowering blood flow in the brain regions linked with anxiety, like the hypothalamus. This region can become overactive during times of high levels of stress & worry.

CBD Stops
That Anxious Feeling

Researchers have found that hemp-derived CBD products promote general feelings of calmness and reduce the feeling of being overwhelmed & anxious for CBD users. The ability to remain calm during these situations allowed their trial patients to have more control over how they reacted. This reaction was based on an explicit choice rather than the automatic response from adrenaline caused by fear hormones such as cortisol.

CBD is Also An

Besides alleviating feelings of stress and worry, CBD and THC also work as natural antidepressants! Researchers have discovered that this natural product stimulates endocannabinoid receptors within depressed patients leading them out of their depression spiral. Additional research and increased clinical trials are just a few of many indications that will lead clinicians into using cannabis-based medications more often than ever before.

CBD boosts levels of:

  • Dopamine
  • Oxytocin
  • Serotonin   
  • Endorphins  

What Exactly is an
Endocannabinoid System?

The endocannabinoid system is responsible for a number of different functions that are vital to your health. It controls things like:

  • Eating Habits
  • Sleeping Patterns
  • Social Behaviors
  • Inflammation
  • Pain Levels
  • Anxiety
  • Skin Diseases

How does it do all this? The Endocannabinoid System (ECS) helps cells communicate by regulating the levels of any chemicals that may be too high or low. In addition, the endocannabinoid system regulates several bodily functions, including signaling brain activity, immunity, and digestion. Understanding the intricacies of this system is one piece in understanding CBD oil as a whole. It consists of a group of molecules and receptors that occur naturally in the body.

The CB2
Receptors Responsibility

CB2 receptors are typically located on immune cells throughout the body. They regulate essential cell functions such as immunity response by managing both pro-inflammatory effects (supporting anti-inflammation) or inflammatory responses when needed. CBD oil works through these receptor sites to manage pain-sensing neurons, eventually stopping them from sending discomfort signals into the nervous system giving this natural therapy its healing power.

Recent studies show that cannabis and hemp have been used for centuries to relieve pain in patients with arthritis, headaches, inflammation, and neuropathic conditions. Hemp is healing without the high!

Suppression of Inflammation

CBD oil goes to work when inflammation is triggered in the body. This powerful cannabinoid binds with CB2 receptors and has various effects on pain, including reducing it peripherally by blocking signals from being sent to your brain. CBD products can also reduce inflammation molecules released during this process, which helps reduce discomfort and swelling at sites of injury or infection!

When Your Immune System Reacts Inappropriately

The inflammatory response is an integral part of how your immune system works, but sometimes it gets activated at the wrong time. When this happens, chronic inflammation can happen, or you might develop auto-immunity and attack healthy cells with your body's natural defenses.

Our bodies are programmed to react when we experience pain. Pain is a natural survival instinct, which means that it should be felt and processed to live our best lives possible. However, this becomes problematic when these signals are improperly triggered. A well-known endocannabinoid called anandamide (AEA) can reduce feelings of intense discomfort. The AEA blocks the transmission of nerve impulses from one cell or neuron to another through messages sent via neurotransmitters.

Anandamide Introduces Balance

Both hemp & a cannabis plant help achieve a sense of balance. It does this by introducing our bodies to anandamide, the "bliss molecule" that binds with CB receptor sites, mimicking natural chemicals in your body and reducing pain-sensing neurons signals while also boosting mood. In addition, when anandamide is modulated with CBD, therapeutic effects are introduced.

Diseases CBD Addresses With Anandamide

  • Neurodegenerative
  • Inflammatory
  • Cardiovascular
  • Liver
  • Gastrointestinal
  • Skin Diseases
  • Pain
  • Psychiatric Disorders
  • Cancer
  • Obesity
  • Metabolic Syndrome
  • Diabetes

What It Means To Regulate The ECS

It is crucial to regulate the immune, nervous and endocrine systems to achieve homeostasis. This helps relieve pain and inflammation by bringing these bodily functions back into balance. The use of CBD oil derived from hemp also affects fat processing and our moods which can lead to an increased energy level while improving brain health (neuro-inflammation).

Another way that this cannabinoid works its magic is through hormone regulation because it has qualities known as adaptogens or substances used specifically for stabilization purposes, such as hormones within your body's system!

Terpenes, The Essential Oils Of All Plants

Terpenes come from organic substances found in flowers & plants. Hemp & cannabis plants have a high concentration of Terpenes, making cannabis so aromatic and flavorful. Terpenes also act as natural pesticides for plants by repelling pests or creating an unfriendly environment for bugs to live in; hemp has a variety of terpene profiles that can help regulate mood, immune response, and inflammation.


Citrus Aroma 
This stress reliever also helps boost your mood. CBD oil may also be helpful for stomach problems.


Piney Aroma
It's been said to improve your memory and help with alertness. It is also anti-inflammatory.


Lavender & Flora Scents
This has a sedative effect and works to help with depression, insomnia, and stress.


Spicy Aroma
Terpenes are rich in antioxidants and anti-inflammatory properties, which can help alleviate the symptoms of pain. It is also helpful against insomnia.


Earth/Woody Aroma
This is yet another terpene that helps to relieve pain and has antibacterial effects on the skin. It also is an appetite suppressant and can sedate while promoting a sense of relaxation.