Understanding CBD:
CB1 Receptors,
CB2 Receptors &
Hemp Terpenes

Cannabidiol (CBD) has been generating a lot of buzz lately. You've probably seen cbd oil for sale at your local dispensary, and many people are wondering what it is and how it differs from cannabis.

Our team here at One Hemp Holistics will help you understand CBD by going over CB1 receptors, CB2 receptors, the benefits of hemp terpenes, as well as some helpful hints to know before you buy!

CB-receptors are two main types of receptors in the human body that interact with cannabinoids. Put simply, they're what CBD interacts with to provide health benefits or produce a cannabis high when THC is present.

CB1 Receptors - Primarily found in your brain

CB2 Receptors - Typically found on immune cells

Understanding CB1 Receptors

CBD and THC circulate through the bloodstream to the brain, where they activate cannabinoid receptors. Cannabis-derived CBD is non psychoactive; instead, it potentiates THC by enhancing its effects at CB1 receptors throughout the body. These effects include a mood boost that renders anxiety less overwhelming (desensitization).

CBD Is True Bliss

CBD has been shown to increase levels of anandamide in the brain, which is one of the few cannabinoids found naturally in the body. The word anandamide was taken from the Sanskrit word Ananda which stands for bliss.

Why CBD Works So Well

The reason CBD products work so well is due to the fact that CBD inhibits FAAH enzymes from breaking anandamide down. As a result, people who take CBD can experience reduced anxiety disorders and other benefits that come with being less anxious thanks to this inhibitory effect on the FAAH enzyme's activity level.

What Is Anandamide?

CBD works to regulate various systems of the body without any negative effects whatsoever. One of these systems is to prevent the FAAH enzyme from breaking down anandamide. Anandamide is the fatty acid neurotransmitter that is responsible for having an effect on many different elements from moods to appetite patterns.

CBD's Healing Powers

  • Pain Relief
  • Body Stiffness & Soreness
  • Chronic Pain
  • Arthritis

Lets Relax
Together With
CBD

CBD is a cannabis-derived substance used to reduce stress and promote relaxation. It works by reducing blood flow in the brain regions linked with anxiety like the hypothalamus. This region can become overactive during times of high levels of stress & worry.

CBD Stops
That Anxious Feeling

Researchers have found CBD promoted general feelings of calmness and reduced their sense they were being overwhelmed when anxious. The ability to remain calm during these situations allowed their trial patients to have more control over how they reacted. This reaction was based on an explicit choice rather than automatic response from adrenaline caused by fear hormones such as cortisol.

CBD is Also An
Antidepressant

Besides alleviating feelings of stress and worry, CBD also works as a natural antidepressant! Researchers have discovered that this natural product stimulates endocannabinoid receptors within depressed patients leading them out of their depression spiral. This is just one among many indications that will lead clinicians into using cannabis-based medications more often than ever before.

CBD boosts levels of:

  •  Dopamine
  • Oxytocin
  • Serotonin   
  • Endorphins  

What Exactly is an
Endocannabinoid System?

The endocannabinoid system is responsible for a number of different functions that are vital to your health. It controls things like:

  • Eating Habits
  • Sleeping Patterns
  • Social Behaviors
  • Inflammation
  • Pain Levels
  • Anxiety
  • Skin Diseases

How does it do all this? The Endocannabinoid System (ECS) helps cells communicate by regulating the levels of any chemicals that may be too high or low. The endocannabinoid system regulates several bodily functions, including signaling brain activity, immunity, and digestion. Understanding the intricacies of this system is one piece in understanding CBD as a whole. It consists of a group of molecules and receptors that occur naturally in the body.

The CB2
Receptors Responsibility

CB2 receptors are typically located on immune cells located throughout the body. They regulate important cell functions such as immunity response by managing both pro-inflammatory effects (supporting anti-inflammation) or inflammatory responses when needed. CBD works through these receptor sites to manage pain sensing neurons which will eventually stop them from sending signals of discomfort into the nervous system giving this natural therapy its healing power.

Recent studies show that cannabis and hemp have been used for centuries to relieve pain in patients with arthritis, headaches, inflammation as well as neuropathic conditions. Hemp is healing without the high!

Suppression of Inflammation

CBD goes to work when inflammation is triggered in the body. This powerful cannabinoid binds with CB2 receptors and has a variety of effects on pain, including reducing it peripherally by blocking signals from being sent to your brain. CBD also reduces inflammatory molecules that are released during this process which can help reduce discomfort as well as swelling at sites of injury or infection!

When Your Immune System Reacts Inappropriately

The inflammatory response is an important part of how your immune system works, but sometimes it gets activated at the wrong time. When this happens, chronic inflammation can happen or you might develop auto-immunity and attack healthy cells with your body's natural defenses. 

Our bodies are programmed to react when we experience pain. Pain is a natural survival instinct, which means that it should be felt and processed in order for us to live our best lives possible. This becomes problematic when these signals are improperly triggered. A well-known endocannabinoid called anandamide (AEA) can reduce feelings of intense discomfort by blocking the transmission of nerve impulses from one cell or neuron to another through messages sent via neurotransmitters.

Anandamide Introduces Balance

The cannabis plant helps achieve a sense of balance. It does this by introducing our bodies to anandamide which is the "bliss molecule" that binds with CB receptor sites, mimicking natural chemicals in your body and reducing pain-sensing neurons signals while also boosting mood. When anandamide is modulated with CBD therapeutic effects are introduced.

Diseases CBD Addresses With Anandamide

  • Neurodegenerative
  • Inflammatory
  • Cardiovascular
  • Liver
  • Gastrointestinal
  • Skin Diseases
  • Pain
  • Psychiatric Disorders
  • Cancer
  • Obesity
  • Metabolic Syndrome
  • Diabetes

What It Means To Regulate The ECS

It is important to regulate the immune, nervous and endocrine systems in order to achieve homeostasis. This helps relieve pain and inflammation by bringing these bodily functions back into balance. The use of CBD derived from hemp also affects fat processing as well as our moods which can lead to an increased energy level while improving brain health (neuro-inflammation).

Another way that this cannabinoid works its magic is through hormone regulation because it has qualities known as adaptogens or substances used specifically for stabilization purposes such as hormones within your body's system!

Terpenes, The Essential Oils Of All Plants

Terpenes come from organic substances found only in plants. These oils are what make cannabis so aromatic and flavorful. Terpenes also act as natural pesticides for plants by repelling pests or creating an unfriendly environment for bugs to live in; hemp has a variety of terpene profiles which can help regulate mood, immune response and inflammation

Limonene

lemon
Citrus Aroma 
This stress reliever also helps boost your mood. CBD may also be helpful for stomach problems.

Pinene

pine
Piney Aroma
It’s been said to improve your memory and help with alertness. It is also anti-inflammatory.

Linalool

lavender
Lavender & Flora Scents
This has a sedative effect and works to help with depression, insomnia, and stress.

Caryophyllene

pepper
Spicy Aroma
Terpenes are rich in antioxidant and anti-inflammatory properties, which can help alleviate the symptoms of pain. It is also useful against insomnia.

Humulene

basil
Earth/Woody Aroma
This is yet another terpene which helps to relieve pain as well as having antibacterial properties. It also is an appetite suppressant and has the ability to sedate while promoting a sense of relaxation.
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