Understanding CBD

CB1 RECEPTORS: Are Found Mostly in the Brain

CBD and THC travel through the bloodstream to the brain and activate the endocannabinoid system. In the brain, even low THC (0.3% and under) binds to CB1 receptors to produce many effects. These effects include heightened mood, and pain relief (desensitization).

CBD also increases anandamide levels in the brain. Anandamide is one of the few cannabinoids found naturally in the human body and stands for Bliss. CBD inhibits the FAAH enzyme, which breaks down anandamide. Thus, CBD can increase anandamide levels by preventing FAAH from breaking it down. Inhibiting the FAAH enzyme has been shown to be a useful strategy for treating anxiety disorders, and some of CBD’s anti-anxiety properties may come from its ability to inhibit this enzyme.

Anandamide is responsible for regulating levels of other chemicals found in the brain, including serotonin and dopamine. By increasing anandamide levels, CBD ultimately regulates other important neurotransmitters as well.

CBD has been known to help relieve pain and stiffness, including chronic pain from arthritis.

ANXIETY / DEPRESSION:

CBD relieves stress and promotes relaxation. Researchers used imaging scans to understand which brain regions are involved with CBD’s anti-anxiety effects. They found that CBD causes a reduction in blood flow to specific regions of the brain linked to anxiety, such as the hypothalamus. These regions typically become overactive in anxiety disorders, whereas CBD seems to quiet their activity.

CBD was also effective at reducing the overall anxiety scores of participants in the study. Besides reducing anxiety, CBD has been found to work as an antidepressant. CBD seems to work to balance dysfunction in the endocannabinoid system of depressed patients. It has also been found to act on
a serotonin receptor that influences symptoms of depression. This has opened the door for clinicians and patients alike seeking alternative ways of treating depression. 
Anandamide is responsible for regulating levels of other chemicals found in the brain, including serotonin and dopamine. By increasing anandamide levels, CBD ultimately regulates other important neurotransmitters as well.

Knowledge is Key:

The endocannabinoid system (ECS), comprised of cannabinoid receptors, endocannabinoid
molecules, and their metabolic enzymes, is a crucial molecular system that the body uses to
help maintain homeostasis.Since its job is homeostasis, which is regulating your body so you
can live comfortably. It is in charge of your eating habits, your sleeping patterns, and even
your social habits. The ECS also controls inflammation, pain, anxiety and skin diseases. It helps
your neurons navigate the neurotransmitters to the right receiver by either elevating the
levels that are too low or decreasing the levels of a hormone that is overabundant.
Everyone has a cell signaling system known as the endocannabinoid system. It consists of agroup of molecules and receptors that occur naturally in the body.

CB2 RECEPTORS: PAIN AND INFLAMMATION

Compounds in cannabis and hemp has been used for thousands of years to treat pain conditions including arthritis, headaches, inflammation, and neuropathic pain. Hemp is healing without the HIGH! CB2 receptors are found on immune cells throughout the body and brain, and are responsible for controlling important cellular functions and for modulating anti-inflammatory effects. CBD and THC have pain killing effects. CBD works to manage pain by acting on the CB2 receptor.

One of these functions involves suppressing the inflammation response produced by the immune system. This reduces the amount of inflammatory molecules, such as cytokines (any class of immunoregulator proteins), that occur at sites of inflammation. CBD binds to CB1 therefore activity in the pain circuits are inhibited, thus resulting in reduced pain and inflammation. Further, by reducing inflammation peripherally, CBD is able to block pain signals from being sent to the brain.

Chronic inflammation and auto-immune diseases are examples of the immune system getting activated inappropriately. When that happens, the inflammatory response lasts too long (which results in chronic inflammation) or gets directed toward healthy cells (which is known as auto-immunity). Endocannabinoids seem to suppress or limit the immune system’s inflammatory signals. One of the most famous endocannabinoids is anandamide (AEA). High levels of AEA can reduce pain, which is what your body uses when you are experiencing pain. However, sometimes your natural chemistry isn’t enough. This is why many people take CBD medication because CBD elevates Anandamide that is already present in your brain.

Studies show that that the endocannabinoid system which is our bodies endogenous (inside the body) system of neuromodulator chemicals and receptors found in the mammalian brain and throughout the body is activated by exogenous (outside the body) compounds naturally occurring in Hemp (Cannabis Sativa L.)By activating the ECS system the body signals molecules in the body known as anandamide and 2-AG to restore balance by inhibiting the enzymes that break them down therefore, modulating this system has therapeutic effects in almost all diseases affecting the human body, including neurodegenerative, inflammatory, cardiovascular, liver, gastrointestinal, skin diseases, pain, psychiatric disorders, cancer, obesity/metabolic syndrome, diabetes and diabetic complication, among many others.

Regulating this system means bringing immune, nervous and endocrine system back to homeostasis which has remarkable effects on pain, inflammation, formation of new nerve cells, fat and sugar processing, mood, energy, brain health (neuro-inflammation) and hormone balance.BUT WHY AND HOW?  BECAUSE CBD DERVIDED FROM HEMP IS AN ADOPTOGEN!!Adaptogens or adaptogenic substances are used in herbal medicine for the claimed stabilization of physiological processes and promotion of homeostasis.They are called adaptogens because of their unique ability to “adapt” their function according to the specific needs of the body. This may be physical, chemical or biological needs.

HEMP IS RICH IN SEVERAL TERPENES: (Essential oils of all plants)


Terpenes are chemicals that give the cannabis plant its unique scent. Even in tiny amounts, terpenes work extremely well with cannabinoids to heal the body. Here are some well-known terpenes:

Limonene: This stress reliever also helps boost your mood. It may also assist with gastric issues.
Pinene: It could potentially improve your memory and boost alertness. It is also anti-inflammatory.
Linalool:
This has a sedative effect and works to help with depression, insomnia, and stress.
Caryophyllene: This terpene is an antioxidant and anti-inflammatory that helps relieve the symptoms of pain. It is also useful against insomnia.
Humulene: This is another pain-relieving terpene which has antibacterial properties and also works as an appetite suppressant.